Output of the month
​4D Liquid-phase Electron Microscopy of Ferritin by Brownian Single Particle Analysis
arXiv:1907.03348 [q-bio.BM]
Lorena Ruiz-Perez, Gabriele Marchello, and Cesare De Pace In collaboration with F. Gervasio (UCL), and Neil Wilikison (Gatan)

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In our labs, we design bionic units that mimic specific biological functions and/or introduce operations that do not exist in Nature. We apply a constructionist approach where we mimic biological complexity in the form of design principles to produce functional units from simple building blocks and their interactions. We called this Molecular Bionics. Such an effort is multidisciplinary and involves inputs from Chemistry, Physics, Material Science and Engineering from one side and Cell and Molecular Biology, Physiology, Immunology, Oncology and Neuroscience from the other side.

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video-rate Liquid phase video of ferritin proteins diffusion in water
(video from L. Ruiz-Perez, C. De Pace)