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Welcome

स्वागत हे

مرحبا 

Bem-Vinda

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ようこそ

ਸਵਾਗਤ ਹੈ

স্বাগত

స్వాగతం

Hoşgeldiniz

Bienvenue

환영

Willkommen

Chào mừng bạn

வரவேற்பு

خوش آمدید

Sugeng rawuh

Benvenuti

સ્વાગત છે

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Maraba

Selamat datang

ยินดีต้อนรับ

Karibu

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Benvingut
Croeso

Καλώς ορίσατε
Välkommen

Velkommen

Witamy

Tere tulemast

JoinUs

Are you interested in applying for a PhD scholarship  or a Postdoctoral fellowship, check here for the program that fits your needs the best and contact us 

Vacancies

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Post-doctoral research fellow in Computational Precision Nanomedicine

@Chengdu(成都市)

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Post-doctoral research fellow in Synthetic Polymer Chemistry

@Chengdu(成都市)

 
 

AboutUs

We are chemists, physicists, mathematicians, engineers, biologists who work alongside to design bionic units that mimic specific biological functions and/or introduce operations that do not exist in Nature. We apply a constructionist approach where we mimic biological complexity in the form of design principles to produce functional units from simple building blocks and their interactions.​ We called such an approach: Molecular Bionics.

 
 
theTeam
Prof Giuseppe Battaglia

Group Leader

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Beppe (short for Giuseppe) is the Chair of Molecular Bionics in the Department of Chemistry at University College London, ICREA Research professor and Group Leader at Institute of Bioengineering of Catalunya

Laurea in Chemical Engineering (UoPalermo)

Ph'D Soft Matter Physics 

(UoSheffield)

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Dr Denis Cecchin

Operation Officer

(London)

SomaServe Chief Technical Officer

(Cambridge)

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Denis manages our labs operations in London and is also in charge of our translational activities. He's the CTO of both our two spin outs: SomaServe ltd and SomaNautix Ltd

Laurea in Pharmaceutical Technology and Chemistry

PhD in Cell and Tissue Engineering

(UoPadova) 

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Dr Clauida Di Guglielmo

Operation Officer

(Barcelona)

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Claudia manages our labs operations in Barcelona. She's an expert in induced pluripotent stem cells and tissue engineering

Laurea in Medical-Pharmaceutical Biotechnology

(UoFerrara)

PhD in Biomedicine

(UoBarcelona) 

MANAGEMENT

Dr Lorena Ruiz-Perez

Deputy Group Leader & Microscopy Lead

(Barcelona)

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Lorena is a Senior Research Fellow  and Electron microscopy facility manager

Licenciatura in Physics

(UoSeville)

PhD in Soft Matter Physics (UoSheffield)

PDRA UoSheffield, UCL

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Dr Joe Forth

Ramsey Fellow & Physical Biology Lead

(London)

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Joe is a 2020 Ramsey research fellow and he's developing novel methods for printing soft materials)

 MSc. In  Physics

 (UoBirstol) 
Ph.D. In Physics  

 (University of Edinburgh) 

PDRA Lawrence Berkeley National Laboratory, UCL

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Dr Mohit Kumar
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Mohit is a Caixa Junior Leader Fellow and is developing out-of-equilibrium nanomaterials for targeted therapy.

​B.Sc. and M.Sc. in Chemistry, (Sri Sathya Sai Institute of Higher Learning) 

Ph.D. in Nanomaterials (Jawaharlal Nehru Centre for Advanced Scientific Research)

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Caixa Junior Leader Fellow & Molecular Engineering

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(Barcelona)

RESEARCH FELLOWS

Dr Diana Lourenço Matias

CRUK PDRF & NanoOncology lead

(London)

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Diana is a Post Doctoral Research Fellow sponsored by the CRUK  in collaboration with Prof Simona Parrinello at the UCL Cancer Institute

B.Sc. in Biochemistry

(UoEvora)

 M.Sc. in Biomedical research

 (UoCoimbra) 
Ph.D. inn in Morphological Sciences 

(UoRio de Janeiro)

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Dr Daniel Gonzalez-Carter

Caixa Junior Leader Fellow

& NanoNeurology lead

(Barcelona)

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Daniel is a Caixa Junior leader postdoctoral fellow 

B.Sci Biochemistry and Biological Chemistry, (UoNottingham)

MSc. Pharmacology (King's College London)

Ph'D in Neuroscience (Imperial College London)

Dr Silvia Acosta Guitierrez

CwCUK PDRF & Comput.&Theory lead 

(London)

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Silvia is a computational physicist working on the design od phenotypic medicine

B.Sci iin Physics

M.Sci Physics

(University of La Laguna. Tenerife (Spain))

Ph'D in Physics

(University of Cagliari)

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Dr Rui Pereira

AIRC iCARE fellow

(Barcelona)

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Rui is a AIRC-iCARE2 research Fellow  working on the development of novel brain tumour models 

B.Sci in Applied Biology 

M.Sc on Processing and Characterization of Materials  University of Minho (PT). 

Ph'D in Tissue Engineering, Regenerative Medicine and Stem Cells

University of Minho (PT)./University of Genoa (IT)

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Dr Catia Lopes Carvalho

ERC PDRF

(Barcelona)

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Catia is a Post Doctoral Research Fellow sponsored under our ERC project.)

BSc in  Pathology, Physiology and Thanatology

(School of Health -P.Porto)

PhD in Neuroscience

 (UoPorto) 

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Dr Iris L. Batalha

Caixa Junior Leader Fellow & NanoImmunology lead 

(Barcelona)

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Iris is a 'La Caixa' Postdoctoral Junior Leader working on the development of targeted nanotherapeutics for drug delivery with a focus on infectious diseases and cancer. 

BSc in Applied Chemistry, MSc in Biotechnology, and PhD in Bioengineering (MIT-Portugal Program) at Universidade NOVA de Lisboa, Portugal. 

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Dr Yangwei Deng (邓扬威)

SomaServe Scientist

(Cambridge)

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Yangwei (邓扬威) ia Post Doctoral Research Fellow sponsored under our ( EP/N026322/1) EPSRC project)

B.E. in Polymer Materials and Engineering

 (Zhejiang University )

Ph.D. in Molecular Chemistry

(PSL Université Paris)

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Dr Virginia Gouveia

SomaServe Scientist 

(Cambridge)

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Virginia is the Formulation specialist in SomaServe ltd

B.Eng in Bioengineering

(U Catolica Portuguesa Porto)

M.Eng in Biomedical Engineering

 (UoPorto)

Ph'D in Pharmaceutical Chemistry

(University College London/UoPorto)

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PhD STUDENTS

Safa Al-Madhi

Self-sponsored Student

(London)

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Safa is working on the characterisation and development of polymersomes chemotactic behaviour

MSci in Pharmaceutical Chemistry

(Queen Mary University of London}

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Chiara Cursi

AZ/EPSRC Student

(London)

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Chiara is working on Precision cancer targeting by combinatorial low-affinity binding​

BSc Molecular Biology 
MSc in Molecular Biology 

(UoPisa)

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Cesare De Pace

DENSsolutions/EPSRC Student

(London)

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Cesare is workin onLive cell Imaging  using liquid-phase scanning transmission electron microscopy

Laurea in Pharmacy

(UoRoma Tor Vergata)

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Miguel (Miko) Sipin

EPSRC Student

(London)

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Miko is working on Development of Personalised Medicine for the Treatment of Brain Tumours​

M.Sc. in Chemistry  

(UoOxford)

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Valentino Barbieri

EPSRC Student

(London)

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Valentino is working on the Development of Bioinspired Phototactic nanorobots in collaboration with  Dr Giorgio Volpe activematterlab.org

 

Laurea. in Materials and Nanotechnology Engineering  

(Politecnico Milano)

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Maryam Al-Ghandi

King Abdullah Sch. Student

(London)

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Maryam is working on the study of biodegradation of polymersomes and micelles

BSc in Chemistry

(Albaha University}

MSc in Analytical and Forensic chemistry

(UoHull)

Barbara Ibarzo Yus

EPSRC Student

(London)

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Barbara is working on Polymersomes for cancer immune-therapy applications.

B.Sc. in Biotechnology 

(UoZaragoza)

MSc Genetics and Cell Biology

(Coputense Madrid)

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Joseph Buckley

ERC Student

(London/Barcelona)

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Joe is working on the Theory and Simulation of Phenotypic Targeting and Super Selectivity .

MSci in Chemistry with Mathematics 

(University College London)

MRes in Fluid Dynamics Across Scales

(Imperial College London)

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Gabriel Ing

Welcome Trust Student

(London)

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Gabriel is working on Liquid phase transmission electron microscopy of RNA polymerase collaboration with the Prof Finn Werner labs

BSc in Biochemistry

 Imperial College London

Junyang Chen
(陈君洋)

Self-sponsored student

(London/Chengdu)

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Junyang is working on the Development of soft random laser for biosensing in collaboration with Ricardo Sapienza at Imperial College London 

B.Sci Biology

Anhui University

MSci Cell Biology

The University of Manchester 

Jiangqi Feng
(冯江琪)

Self-sponsred Student

(London/Chengdu)

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Jangqi is working on the mechanism and therapy of BBB inflammation 

 

B.Eng. Biopharmaceutics 

(Nanjing University of Chinese Medicine)

MSc in Pharmaceutics

(University College London)

Melis Pisiren

BBSRC/AZ Student

(London)

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Melis is working on the study of macromolecular transport across the blood-brain barrier in collaboration with Astrazeneca 

 

BSci. in Genetics

(UoGlasgow)

MRes. Neuromuscular Diseases

(University College London)

Barbara Borges

ERC Student

(Barcelona)

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Barbara is working on the study of active transport in reactive vesicles

BEng Chemical Engineering 
MEng Mechanical Engineering (Federal University of Minas Gerais - UFMG)
MSci Nanoscience and Nanotechnology

(KU Leuven & University of Barcelona)

Lara Aiassa

ERC Student

(Barcelona)

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Lara is working on the study of the pathophysiology of Tuberculosis in order to decipher the host-pathogens interactions d in collaboration with Prof. Loris Rizzello.

B.Eng Biomedical Engineering

Universidad Nacional de Córdoba 
M.Sci in Bionanotechnology

(Politecnico di Torino)

Jose Maria Muñoz López

FPI Student

(Barcelona)

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Jose is working on the design of novel antiviral nanoparticles.

BSc in Chemistry (Universidad Autonoma Barcelona) MSc in Organic Chemistry (Universidade Federal de Minas Gera)

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Gian Marco Tuveri

ERC Student

(Barcelona)

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Gian is working on on the optimisaiton of computational and experimental methods for studying protein structure in liquid water using TEM

Laura in Physics  
(Università di Cagliari)

MASTER, VISITING, AND UG STUDENTS

 
Outputs
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Selected publications

  •  X. Tian, D. Moreira-Leite, E. Scarpa, S. Nyberg, G. Fullstone, J. Forth, D. Lourenco-Matias, A. Apriceno, A. Poma, A. Duro-Castano, M. Vuyyuru, L. Harker-Kirschneck, A. Saric, Z.Zhang, P. Xiang, B. Fang, Y. Tian, L. Luo, L. Rizzello, G. Battaglia* On the shuttling across the blood-brain barrier via tubules formation: mechanism and cargo avidity bias Science Adv. 2020, 6 (48), eabc4397

  • I. Williams*, S. Lee, A. Apriceno,R. P. Sear, G. Battaglia* Diffusioosmotic and convective flows induced by a non-electrolyte concentration gradient Proc. Natl. Acad. Sci. USA 2020, 17, 25263-25271

  • M. Liu, A. Apriceno, M .Sipin, E. Scarpa, L. Rodriguez-Arco, A. Poma, G. Marchello, G. Battaglia*, S. Angioletti-Uberti* Combinatorial entropy behaviour leads to range selective binding in lig- and receptor interactions Nature Comm. 2020 11, 4836

  • X. Tian , C. De Pace, L. Ruiz-Perez, D. Chen, R. Su, M. Zhang, R. Zhang, Q. Zhang, Q. Wang, H. Zhou, J. Wu, Z. Zhang*, Y. Tian*, and G. Battaglia* A Cyclometalated Iridium (III) Complex as a Microtubule Probe for Correlative Super-Resolution Fluorescence and Electron Microscopy Adv. Mater., 2020, 32, 2003901 

  • F. Fenaroli, J. D. Robertson, V. Gouveia, C. Di Guglielmo, C. De Pace, E. Scarpa, P. M Elks, D. Evangelopoulos, J. Ortiz Canseco, S. Yona, H. M Marriott, D. H Dockrell, S. Foster, T. McHugh, S. A Renshaw, J. Samitier, G. Battaglia* and L. Rizzello* Polymersomes Eradicating Intracellular Bacteria ACS Nano 2020, 14, 7, 8287–8298

  • X. Tian, S. Angioletti-Uberti, G. Battaglia* On the design of precision nanomedicines. Science Adv. 2020, 6, 4 , eaat0919

  • Y. Zhu, A. Poma, L. Rizzello, V. Goueveia, L. Ruiz-Perez, G. Battaglia*,and C.K. Williams* Metabolic active fully hydrolysable polymersomes Angew. Chem. Int. Ed. 2019, 8, 4581 –4586

  • A. Joseph, C .Contini, D. Cecchin, S. Nyberg, L .Ruiz-Perez, J. Gaitzsch, G. Fullstone, J. Azizi, J. Preston, G. Volpe, G. Battaglia* Chemotactic synthetic vesicles: design and applications in blood brain barrier crossing Science Adv., 2017, 3, 8, e1700362 

  •  L. Messager, J. Kim, J. Burns, D. Cecchin, J. Hindley, J. Gaitzsch, G. Battaglia*, S. Howorka* Biomimetic nanoreactors composed of polymersomes, membrane spanning DNA nanopores, and encapsulated enzymes Angew. Chem. Int. Ed, 2016, 37, 11272-11275

  • L. Ruiz Perez, L. Messager, J. Gaitzsch, A. Joseph, L. Sutto, F. L. Gervasio and G. Battaglia* Molecular engineering of polymersome surface topology Science Adv. 2016, e1500948

  • P. Viswanathan, M. Ondeck, S. Chirasatitsin, K. Nghamkham, D. Cecchin, G. C. Reilly, A. J. Engler* and G. Battaglia* 3D Surface Topology Guides Stem Cell Adhesion and Differentiation Biomaterials 2015, 52, 140–147

  • J. D. Robertson ,G. Yealland, M. Avila-Olias, L. Chierico, O. Bandman, S. A. Renshaw, G. Battaglia* pH sensitive tubular polymersomes: formation and applications in cellular delivery ACS Nano, 2014, 8, 4650–4661

  • A. Blanazs, J. Madsen, G. Battaglia*, A. J. Ryan* and S. P. Armes* Mechanistic Insights For Block Copolymers Morphologies: How Do Worms Form Vesicles? J. Am. Chem. Soc. 2011 133 (41), 16581–16587

  • M. R. Gill, J. Garcia-Lara, S. J. Foster, C. Smythe, G. Battaglia* and J. A. Thomas* A Ruthenium(II) Polypyridyl Complex for Direct Imaging of DNA Structure in Living Cells Nature Chem. 2009, 1, 662 - 667

  • H. Lomas, I. Canton, S. MacNeil, J. Du, S.P. Armes, A.J. Ryan, A.L. Lewis and G. Battaglia* Biomimetic pH Sensitive Polymersomes for Efficient DNA Encapsulation and Delivery, Adv. Mater. 2007, 19, 4238–4243

 
ArtScience