We are interested in how molecules, macromolecules, viruses, vesicles, and whole cells traffic across our body barriers. We combine novel microscopic tools with theoretical and computational physics to study biological transport from the single molecules, cell membrane, to the whole organ- ism. We thus translate the acquired knowledge to bioengineer novel nanomedicines, combining soft matter physics with synthetic chemistry. Here, we design bionic units that mimic specific bio- logical functions and introduce operations that do not exist in nature. We apply a constructionist approach where we mimic biological complexity in the form of design principles to produce func- tional units from simple building blocks and their interactions. We call such an effort, Molecular Bionics, and it involves inputs from physical science and engineering from one side and biomedical sciences.